EDITORIAL COMMENT

Transperineal prostate biopsy (TPB) is a sterile alternative to transrectal biopsy (TRUS-Bx). In addition, improved anterior-apical sampling and high cancer detection rate are area of interest for TPB. In the present study, the authors published 10 years of experience in 3007 TPB patients. Overall reported prostate cancer (PCa) detection rate was 35.5%. The PCa detection rate in the apex (52%) was higher than the average cancer detection rate in 10 defined regions (p=0.014). Anti-thrombotic treatment was not discontinued in the study population before TPB. Postoperative hematuria (47%) and hematospermia (6.1%) were the most frequent complications after biopsy. Perineal hematoma development was reported in 0.5% (n=16) of patients. Only one case of sepsis was reported in a long-term indwelling catheter patient. PCa was more common in transition zone. The present study demonstrated that transition zone cancer detection is statistical significantly higher with TPB. Particularly it is important for the re-biopsy patients. TPB is safe for patients with high risk of sepsis and for anti-thrombotic users.