Urologic Survey (Endourology)

Re: Comparison of Partial Nephrectomy and Percutaneous Ablation for cT1 Renal Masses

10.4274/jus.2015.01.013

  • Yakup Kordan

J Urol Surg 2015;2(1):45-45

Partial nephrectomy (PN) and radical nephrectomy achieves similar oncological outcomes for cT1 renal tumors and European Association of Urology (EAU) guideline suggested PN for cT1 tumors whenever technically feasible. EAU guideline state that percutaneous ablation therapy should be limited for comorbid patients with small renal masses. Previous studies were controversy, percutaneous ablation therapy had similar or lower recurrence free survival rate when compared with PN. In this study the authors for the first time compared oncological outcomes of two different percutaneous ablation therapies including radiofrequency ablation (RFA) and cryoablation with PN for cT1 tumors. There were 1424 patients treated with PN (n=1057), RFA (n=180) and cryoablation (n=187) for T1a tumors and 379 patients treated with PN (n= 326) and cryoablation (n=53) for T1b renal tumors. Local recurrence-free survival rate at 3 year was similar among three therapy (98%) for T1a tumors. PN (99%) and cryoablation (100%) were significantly better metastases-free survival rates at 3 year compared with RFA (93%) for cT1a tumors. For T1b tumors local recurrence free survival rates and distant metastases free survival rates were similar at 3 year for PN (96%, 96% respectively) and cryoablation (97%, 92% respectively). PN (93%) had higher overall survival rates at 3 year for T1b patients compared with cryoablation (74%) (p