ABSTRACT
Zinner’s syndrome (ZS) was first described by Zinner in 1914. It includes unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction. ZS treatments ranging from medical drug therapy to laparoscopic interventions have been tried in the literature. The 21-year-old patient presented with scrotal pain after ejaculation. The diagnosis was ZS, and the patient underwent transperitoneal laparoscopic left seminal vesicle cyst excision. After two years, transurethral ejaculatory duct resection (TUR-ED) was performed at a single center because of symptomatic dilatation in the seminal vesicles. The patient’s 1-year urological follow-up after TUR-ED remained normal. This presentation is a case report of a single patient and two cases that are rare in the literature. Cyst aspiration and seminal cyst excision may be considered as first-line treatment options, but the possibility of recurrence should not be forgotten. Even if seminal cyst excision is performed, it should be kept in mind that TUR-ED may be required.