EDITORIAL COMMENT

In this meta-analysis, the authors compared outcomes of intracytoplasmic sperm injection (ICSI) using ejaculated versus testicular sperm in men with cryptozoospermia. They also assessed the number of oocytes and maternal and paternal ages. The analysis of a total of 272 ICSI cycles and 4,596 injected oocytes in 5 cohort studies included. Pregnancy and fertilization rates were not statistically different between testicular and ejaculated sperm groups. Although maternal age and paternal age were higher in testicular sperm group, there was no significant difference in the number of oocytes retrieved between the groups. In conclusion, the meta-analysis of 5 studies showed no better pregnancy outcome using testicular sperm for ICSI compared to ejaculated sperm in men with cryptozoospermia.